The pathway with the name 2,4-Dichlorophenol Biodegradation
has the following structure:
Result:
C1=C(C=C(C(=C1)O)Cl)Cl
no rule associatedC1=C(C=CC(=C1)O)Cl
C1=C(C(=C(C=C1Cl)O)O)Cl
C(=C/C(=O)[O-])/C=C(\C(=O)[O-])/Cl
no rule associatedC/1=CC(=O)O\C1=C\C(=O)[O-]
C(=C(\CO)/Cl)/C=C(/C(=O)O)\O
no rule associatedC(=C\CO)/C=C(/C(=O)O)\O
C1=C(C=C(C(=C1)O)O)O
no rule associatedC(=C/C(=O)O)/C(=O)CC(=O)O
C1=C(C=CC(=C1)O)Cl
no rule associatedC1=C(C=C(C(=C1)O)O)O
C1=CC(=C(C=C1)O)O
no rule associatedC1=CC(=C(C(=C1)O)O)O
C(=C\CO)/C=C(/C(=O)O)\O
C1=C(C(=C(C=C1Cl)O)O)Cl
no rule associatedC(=C(\CO)/Cl)/C(=C(/C(=O)O)\O)/Cl
C1=C(C=C(C(=C1)O)O)Cl
C1=C(C=CC(=C1)O)Cl
no rule associatedC1=CC=C(C=C1)O
C1=C(C=C(C(=C1)O)O)Cl
C1=CC=C(C=C1)O
C1=C(C=C(C(=C1)O)O)Cl
no rule associatedC1=CC(=C(C=C1)O)O
C(=C(\CO)/Cl)/C(=C(/C(=O)O)\O)/Cl
C1=C(C=C(C(=C1)O)O)Cl
no rule associatedC(=C(\CO)/Cl)/C=C(/C(=O)O)\O
C/1=CC(=O)O\C1=C\C(=O)[O-]
no rule associatedC(=C/C(=O)O)/C(=O)CC(=O)O
C(=C/C(=O)O)/C(=O)CC(=O)O
no rule associatedC(CC(=O)O)C(=O)CC(=O)O
C1=C(C=C(C(=C1)O)O)Cl
no rule associatedC(=C/C(=O)[O-])/C=C(\C(=O)[O-])/Cl
Description: 2,4-Dichlorophenol is a chlorinated phenolic compound used in the production of herbicides, antiseptics, and other industrial chemicals. Due to its widespread use and resistance to degradation, it often accumulates in soil and water, posing environmental and health risks. Several bacterial species have been identified that can degrade 2,4-dichlorophenol, utilizing it as a carbon and energy source. The degradation typically proceeds through either aerobic or anaerobic pathways, involving specific enzymes that catalyze each step.
Under aerobic conditions, 2,4-dichlorophenol os hydroxylated by phenol hydroxylase to form chlorocatechol derivatives. The chlorocatechol undergoes ring cleavage via catechol 1,2-dioxygenase and catechol dioxygenase, leading to the formation of intermediates that enter the TCA cycles. Felisha et al, 2020
Under anaerobic conditions, 2,4-dichlorophenol is dechlorinated to form 4-chlorophenol. 4-chlorophenol is further dechlorinated to phenol. Phenol is carboxylated to form benzoate. Benzoate is degraded via acetate to methane and carbon dioxide. Zhang et al, 1990
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